(14 customer reviews)


Designed to support and boost the function of the body’s defences against stress.

Scientifically formulated to:

  • Help promote a healthy response to everyday stress, over-work and fatigue;*
  • Help support normal levels of mental clarity, concentration and alertness;*
  • Help support normal levels of vigor and performance;*
  • Non-GMO / Gluten Free / Vegetarian / Vegan.

In stock




No matter what your schedule looks like, chances are you’ve experienced one of those days before. The one where time disappears before your eyes, people are upsetting you for no reason, or your workload is piling higher than humanly possible. Your energy might be plummeting and your patience might be wearing thin. The result is always the same: a tsunami of stress.


To you, stress may look like panic attacks, the overwhelming feeling of sadness, depression or symptoms of anxiety. Sometimes, it may even look like insomnia or hypersomnia. However, stress manifests in your day-to-day life, the natural YUUTO® DESTRESS Anti-Anxiety/Stress formula will press pause on those negative feelings to help you find your balance again.


YUUTO® DESTRESS Anti-Anxiety/Stress formula is an advanced dietary supplement that works to provide the nutritional support your body needs to combat the negative side effects of stress, anxiety, fatigue and other mood-related issues. Each veggie capsule contains a potent blend of vitamins, minerals, herbals and botanicals to stabilise your mood while keeping you alert and focused. Additionally, YUUTO® DESTRESS will keep your brain in good health by clearing the fog of stress and giving you the energy you need to tackle the day. At the same time, you will feel more relaxed, meaning you don’t have to burst a blood vessel while you’re sitting in traffic!


Don’t let the negative effects of stress, anxiety, fatigue and other mood related issues impact your day anymore. Whatever the cause is, let YUUTO® DESTRESS Anti-Anxiety/Stress formula give your stress wings, and let it fly away.

Health benefits, based on science:

  • Helps promote a healthy response to everyday stress, over-work and fatigue;*
  • Helps support normal levels of mental clarity, concentration and alertness;*
  • Helps support normal levels of vigor and performance.*

Real Reviews From Real Customers

Check out some of our customer reviews…


We have compiled a list of the most frequently asked questions here, with answers by our panel of experts.

YUUTO® DESTRESS ANTI-ANXIETY/STRESS* formula is a natural blend of herbs and nutrients designed to provide powerful defence from the mental and physical factors associated with occasional stress. The formula synergistically supports mental relaxation while counteracting the metabolic effects of occasional stress.*


B-Complex Vitamins: B1, B2, B3, B5, B6, biotin (B7)

B vitamins are a group of nutrients that play many important roles in your body. B-complex vitamins are often used to reduce fatigue and boost mood. B-complex vitamins may relieve stress, boost cognitive performance and reduce symptoms of depression and anxiety, even in people without B vitamin deficiencies.*

MINERALS: Calcium Carbonate, Magnesium Oxide, Zinc Oxide, Potassium Gluconate

Minerals play important roles in maintaining blood pressure, fluid and electrolyte balance and bone health; making new cells; delivering oxygen to cells; contributing to normal muscle and nerve functioning.*

Magnesium is a necessary mineral for human health. Magnesium plays a critical role in brain function and mood, and low levels are linked to an increased risk of depression. Magnesium deficiency may lead to anxiety symptoms.

Rhodiola ExtractRhodiola is a mildly stimulating adaptogen, antidepressant, and nootropic agent that has been accepted in the Russian Pharmacopoeia since 1969.  There have been a number of human studies showing that ingestion of this herb can improve exercise endurance, reduce mental fatigue, and enhance cognitive function; lower levels of C-reactive protein and creatine kinase; and benefits work performance.* [1][2][3]

Adaptogens help to re-regulate the HPA axis and sympathoadrenal system (SAS). These control systems maintain normal endocrine, immune, and nervous system function. This makes these herbs useful for treating chronic stress, elevated cortisol levels, depression, insulin resistance, and chronic fatigue immune deficiency syndrome.* [4][5][6][7][8][9][10]

A number of in vitro and in vivo studies show that rhodiola is cardioprotective, antiarrythmic, reduces stress-induced cardiac damage, and decreases myocardial catecholamine levels. It also reduces C-reactive protein levels, a major risk factor for heart disease and atherosclerosis.* [11][12][13][14][15][16][17][18][19][20][21][22][23][24]

Lutein – Researchers at the University of Georgia (Athens, GA) recently published a study that found that macular carotenoids lutein and zeaxanthin isomers may help to lower psychological stress levels and reduce serum cortisol. Chronic stress affects millions of people worldwide and has been linked to a variety of health issues, including high blood pressure, heart disease, depression, and anxiety. These results come part of the LAMA II (Lutein, Vision, and Mental Acuity II) study and are now published in the journal Nutritional Neuroscience.

In this study, the researchers sought to determine whether there is a link between MPOD and psychological stress level, serum cortisol, and symptoms of suboptimal emotional and physical health. Suboptimal mental conditions such as anxiety and depression are both greatly impacted by stress, indicating that although the two are discrete disorders, they share a common root in psychological stress. While lutein and zeaxanthin isomers have previously proven beneficial to eye health, the researchers hoped that the LAMA II study would show the extent to which lutein and zeaxanthin isomers might relieve psychological stress. [25]

Ashwagandha – Root is used in Ayurvedic and Unani medicine as an aphrodisiac, a calming tonic for exhaustion, neurasthenia, anxiety, depression, impaired memory, poor muscle tone, and as an aid in recovery from debilitating diseases. It is given in milk to children and the elderly for emaciation, debility, and anemia.* Calming adaptogen, for CFS, anxiety with hypertension, insomnia, stress-induced ulcers, and impotence associated with anxiety or exhaustion.* [26][27][28][29][30][31][32]

Chamomile – Studies have shown chamomile to be effective in aiding with relaxation, and also helping with anxiety, depression and insomnia.*

GABA – Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. Studies indicate that it promotes positive mood, supports relaxation and moderates occasional stress.*

Lemon Balm – Has calming effects so it helps for anxiety, sleep problems and restlessness.*

Skullcap – Is the anxiety remedy for people who experience anxiety along with restlessness, muscle tension, and jaw clenching. *

Hawthorn – Is used for diseases of the heart and blood vessels such as congestive heart failure (CHF), chest pain, and irregular heartbeat. *

Bacopa (Brahmi) – Supplementing Bacopa has been shown to improve cognition, by means of reducing anxiety. It is also reliable for improving memory formation.*

Magnolia – Has been used for centuries to address anxiety and nervous tension and to promote sleep. *

Passion Flower – It appears to boost the level of gamma-aminobutyric acid (GABA) in your brain and lowers brain activity, which may help you relax and sleep better.*

Valerian – Is most commonly used for sleep disorders (insomnia), anxiety and psychological stress.* Valerian contains a number of compounds that may help promote calmness by reducing GABA breakdown, improving stress response and maintaining adequate levels of mood-stabilizing brain chemicals.*

L-Theanine – The amino acid L-theanine is an effective treatment of moderate and severe anxiety and does not cause drowsiness.*

Oat Straw (Avena Sativa) – Has been used since the Middle Ages to support mental health, especially to combat anxiety and balance mood.*

Mucuna Pruriens – Is especially beneficial to brain health, its primary compound “levadopa (L-dopa)” is a precursor to dopamine, adrenaline and noradrenaline.*

St John’s Wort – Lowers levels of the stress hormone cortisol and enhances the activity of gamma-aminobutyric acid (GABA), a naturally occurring tranquilizer in the brain.*

Hops – Scientific study has demonstrated that both valerian and hops can help alleviate restlessness and anxiety.*

Griffonia Seed Extract 5-HTP – Is a natural way to promote a relaxed mood, while reducing stress-induced food cravings and supporting better sleep. 5-hydroxytryptophan (5-HTP) is a neurotransmitter. It’s a precursor to serotonin. That’s the “happiness neurotransmitter” in the human brain.*

  • Anyone with anxiety;
  • Anyone with clinical depression;
  • Anyone having panic attacks;
  • Anyone having an overwhelming feeling of sadness;
  • Anyone with diminished interest or pleasure in activities;
  • Anyone with insomnia or hypersomnia;
  • Anyone with thoughts of death or suicidal intentions;
  • Anyone suffering from stress.

As a dietary supplement take two (2) veggie capsules once a day. For best results take 20-30 min before bedtime with an 8 oz. glass of water or as directed by your healthcare professional. Everyone is different, and results will vary from person to person. The key is to maintain consistent use every day to see best results. You may want to set a reminder on your phone or computer to make sure you take your supplements at correct time.

Most people experience the relaxing effects of DESTRESS™ the first day they take it, often within 30 minutes. It usually induces a feeling of calm, and won’t make you feel tired. For most people, they just feel good after taking DESTRESS™. It tends to keep you feeling relaxed throughout the day and also usually helps with sleep.* Everyone experiences different levels of anxiety. Some people may need longer to feel the effects of this supplement. We recommend giving this supplement a full 30 days to assess its effects.*

  • Supplement Facts

  • Serving Size2 Veggie Capsules
  • Servings Per Container30
  • Calories0
  • Calories from Fat0
  • Food ComponentAmount/Serving% Daily Value*
  • Vitamin B112 mg800%
  • Vitamin B212 mg700%
  • Vitamin B516 mg160%
  • Vitamin B68 mg400%
  • Niacin28 mg140%
  • Biotin300 mcg100%
  • Calcium Carbonate25 mg3%
  • Magnesium Oxide25 mg6%
  • Zinc Oxide25 mg160%
  • Potassium Gluconate 25 mg
  • Anti-Anxiety and Anti-Stress Proprietary Blend830 mg
  • Rhodiola Ext Sal 1% HPLC, Lutein 5%, Ashwagandha, Chamomile, gamma-Aminobutyric acid GABA, Lemon Balm (balm mint), Skullcap, Hawthorn, Bacopa (Brahmi), Magnolia, Passion Flower, Valerian, L-Theanine, Oat Straw (Avena Sativa) 20:1, Mucuna Pruriens 14% HPLC, St John’s Wort, Hops, Griffonia Seed Extract 5-HTP

Inactive Ingredients: Cellulose (Vegetable Capsule), Rice Flour, Magnesium Stearate, Silicon Dioxide.

  • 100% All Natural
  • Suitable for Vegans: Yes
  • Suitable for Vegetarians: Yes
  • Vegetarian Capsule: Yes
  • Third Party Tested: Yes
  • 60 Veggie Capsules: 1 Month Supply
  • Non-GMO / Dairy Free / Gluten Free / Wheat Free: Yes/Yes/Yes/Yes
  • U.S.A manufactured in a GMP facility.
  • Yuuto™ Nutrition proudly uses only the highest quality ingredients.

CAUTION: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

The Supplement Facts labeling information contained within this website should be regarded as the most up to date and may differ from product labeling that you have purchased. Please consult your product package for information, including allergens, specific to the product you have purchased.

This information is not intended to replace orthodox medical treatment, but is offered as additional, complementary information. Food supplements must not be used as a substitute for a varied, nutritional and balanced diet.

If you are pregnant, breastfeeding, taking any medication or are currently undergoing medical advice, please consult a doctor or healthcare professional before use. Refrain from taking the food supplements if adverse reactions occur and consult a doctor.

Keep out of reach of young children.

Do not use if the goods are received without a tamper strip securely in place.

[1] Acute Rhodiola rosea intake can improve endurance exercise performance. De Bock K1, Eijnde BO, Ramaekers M, Hespel P.
[2] Rhodiola rosea in stress induced fatigue–a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty. Darbinyan V1, Kteyan A, Panossian A, Gabrielian E, Wikman G, Wagner H.
[3] A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work. Phytomedicine. 2003 Mar;10(2-3):95-105. Shevtsov VA, Zholus BI, Shervarly VI, Vol’skij VB, Korovin YP, Khristich MP, Roslyakova NA, Wikman G.
[4] Extract of Rhodiola rosea radix reduces the level of C-reactive protein and creatinine kinase in the blood. Abidov M, Grachev S, Seifulla RD, Ziegenfuss TN. Bull Exp Biol Med. 2004 Jul;138(1):63-4.
[5] Stimulating effect of adaptogens: an overview with particular reference to their efficacy following single dose administration. Phytother Res. 2005 Oct;19(10):819-38. Swedish Herbal Institute
[6] Adaptogens: Herbs for Strength, Stamina, and Stress Relief. Winston & Maimes, 2007
[7] Effect of a combination of extract from several plants on Cell-mediated and humoral immunity of patients with advanced ovarian cancer. Kormosh N, Laktionov K, Antoshechkina M., Phytother Res. 2006 May;20(5):424-5.
[8] The Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood Symptoms. Cropley M, Banks AP, Boyle J. Phytother Res. 2015 Dec;29(12):1934-9. doi: 10.1002/ptr.5486. Epub 2015 Oct 27.
[9] Stress management and the role of Rhodiola rosea: a review. Anghelescu IG, Edwards D, Seifritz E, Kasper S. Int J Psychiatry Clin Pract. 2018 Nov;22(4):242-252. doi: 10.1080/13651501.2017.1417442. Epub 2018 Jan 11.
[10] Therapeutic effects and safety of Rhodiola rosea extract WS® 1375 in subjects with life-stress symptoms–results of an open-label study. Edwards D, Heufelder A, Zimmermann A. Phytother Res. 2012 Aug;26(8):1220-5. doi: 10.1002/ptr.3712. Epub 2012 Jan 6.
[11] Multicenter, open-label, exploratory clinical trial with Rhodiola rosea extract in patients suffering from burnout symptoms. Siegfried Kasper and Angelika Dienel. Neuropsychiatr Dis Treat. 2017; 13: 889–898.
[12] A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue. Olsson EM, von Schéele B, Panossian AG. Planta Med. 2009 Feb;75(2):105-12. doi: 10.1055/s-0028-1088346. Epub 2008 Nov 18.
[13] Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial. Lekomtseva Y, Zhukova I, Wacker A. Complement Med Res. 2017;24(1):46-52. doi: 10.1159/000457918. Epub 2017 Feb 17.
[14] The Nature of Clinical Depression: Symptoms, Syndromes, and Behavior Analysis. Jonathan W Kanter, Andrew M Busch, Cristal E Weeks, and Sara J Landes. Behav Anal. 2008 Spring; 31(1): 1–21.
[14] Neurobiological mechanisms in major depressive disorder. Marije aan het Rot, PhD, Sanjay J. Mathew, MD, and Dennis S. Charney, MD. CMAJ. 2009 Feb 3; 180(3): 305–313.
[15] Monoamine oxidase inhibition by Rhodiola rosea L. roots. van Diermen D, Marston A, Bravo J, Reist M, Carrupt PA, Hostettmann K. J Ethnopharmacol. 2009 Mar 18;122(2):397-401. doi: 10.1016/j.jep.2009.01.007. Epub 2009 Jan 9.
[16] Panax ginseng, Rhodiola rosea and Schisandra chinensis. Chan SW. Int J Food Sci Nutr. 2012 Mar;63 Suppl 1:75-81.
[17] Mood disorders and complementary and alternative medicine: a literature review. Naseem Akhtar Qureshi and Abdullah Mohammed Al-Bedah. Neuropsychiatr Dis Treat. 2013; 9: 639–658. Published online 2013 May 14.
[18] Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression. Darbinyan V, Aslanyan G, Amroyan E, Gabrielyan E, Malmström C, Panossian A.Nord J Psychiatry. 2007;61(5):343-8.
[19] Rhodiola rosea versus sertraline for major depressive disorder: A randomized placebo-controlled trial. Phytomedicine Volume 22, Issue 3, 15 March 2015, Pages 394-399
[20] Exercise, Nutrition and the Brain. Romain Meeusen. Sports Med. 2014; 44(Suppl 1): 47–56. Published online 2014 May 3.
[21] Sleep deprivation: Impact on cognitive performance. Paula Alhola and Päivi Polo-Kantola.
[22] A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work. Phytomedicine. 2003 Mar;10(2-3):95-105.
[23] A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Spasov AA, Wikman GK, Mandrikov VB, Mironova IA, Neumoin VV. Phytomedicine. 2000 Apr;7(2):85-9.
[24] Rhodiola rosea for physical and mental fatigue: a systematic review. Ishaque S, Shamseer L, Bukutu C, Vohra S. BMC Complement Altern Med. 2012 May 29;12:70.
[25] Stringham NT et al. “Supplementation with macular carotenoids reduces psychological stress, serum cortisol, and sub-optimal symptoms of physical and emotional health in young adults.” Nutritional Neuroscience. Published online February 15, 2017.
[26] Adaptogens: Herbs for Strength, Stamina, and Stress Relief. Winston & Maimes, 2007
[27] Direct evidence for GABAergic activity of Withania somnifera on mammalian ionotropic GABAA and GABAρ receptors. J Ethnopharmacol. 2015 Aug 2;171:264-72. doi: 10.1016/j.jep.2015.05.058. Epub 2015 Jun 9.
[28] A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012 Jul;34(3):255-62.
[29] Naturopathic care for anxiety: a randomized controlled trial ISRCTN78958974. PLoS One. 2009 Aug 31;4(8):e6628. doi: 10.1371/journal.pone.0006628.
[30] A double-blind, placebo-controlled evaluation of the anxiolytic efficacy ff an ethanolic extract of withania somnifera. Indian J Psychiatry. 2000 Jul;42(3):295-301.
[31] A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012 Jul;34(3):255-62.
[32] A double-blind, placebo-controlled evaluation of the anxiolytic efficacy ff an ethanolic extract of withania somnifera. Indian J Psychiatry. 2000 Jul;42(3):295-301.



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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. * Results may vary from person to person, any and all supplements should be used in conjunction with a balanced and healthy diet. If you are unsure about taking supplements consult a doctor or pharmacist before use. To ensure your receipt of genuine Yuuto™ products, purchase only through your YuutoNutrition Independent Distributor or through

Additional information

Weight 0.97 kg
Dimensions 6 × 6 × 11 cm
Health Interests

Boost Energy Levels, Brain Health, Stress and Anxiety


Adults, Old-Aged


Botanicals, Herbals, Minerals, Vitamins

Product Type

Veggie Capsules


100% Natural, Gluten-Free, GMP Certified, Non-GMO, Vegan, Vegetarian, Wheat-Free




Yuuto™ Nutrition


  1. Kieran (verified owner)

    Very helpful customer service. After I ordered, I saw that I could save some money if I subscribe, so I called them. They refund the difference so I saved 15%.Happy days!!!!!

  2. Ezekiel S. (verified owner)

    Excellent product!!! I paid for 2 working days delivery, but arrived next day…Very nice packed, easy to swallow, no side effects so far.

  3. Maggie B (verified owner)

    Capsules smaller than I was expecting which is a good thing as I have a bit of trouble with swallowing big pills:)) A great stress reliever.

  4. Naomi (verified owner)

    A natural solution to fight with the stress, definitely will buy again it helps keep under control my anxiety.

  5. Douglas (verified owner)

    I was given few capsules by a friend , to try them and now use them regularly.Highly recommend them.

  6. Corey Davidson (verified owner)

    Really notice a difference in my mood since I take it and delivery is fast every time.

  7. Matthew (verified owner)

    Pleasantly surprised with the effects of this product.Delivery was faster than expected too.

  8. Gemma (verified owner)

    It’s my go to supplement whenever I am feeling stressed out.High quality product I will order again.

  9. Annelie (verified owner)

    I am all for natural supplements. This is an excellent product, contains the best herbs for relaxation, check the label.

  10. Elijah (verified owner)

    I was skeptical, but it works!Helps me cope with day by day stress.

  11. Lucas P (verified owner)

    I am glad I found a natural solution to enhance my mood .Use it for anxiety.Works brilliant for me!

  12. Jalil (verified owner)

    I have tried a few different anti-anxiety types of supplements; this one REALLY works! The intrusive anxiety prone thoughts are much easier to deal with and I feel as though the issue at hand is manageable instead of overwhelming. I highly suggest them to anyone that deals with higher than usual anxiety. Thank you Yuuto, I will be a customer for life.

  13. Harper (verified owner)

    Works great!One of the best over the counter remedies for stress and anxiety.

  14. Kaya Blevins (verified owner)

    This is by far the most effective and least expensive of all I have tried. Excellent product.

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