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Alpha-Lipoic Acid Health Benefits, All Backed by Science

Alpha-Lipoic Acid Health Benefits, All Backed by Science

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What are the Benefits of Alpha-Lipoic Acid?

  • Helps in weight loss
  • Contains antioxidant effects
  • Fights signs of skin aging
  • Protects against radiation damage
  • Potential aid for diabetes
  • Beneficial to your heart health
  • May reduce nerve pain

As an antioxidant, Alpha-lipoic acid (ALA) is responsible for many health benefits in your body. So, what is in this organic compound that makes it a potential remedy in treating a variety of health conditions?

Well, examine these evidence-based benefits it provides.

The first thing you need to know about ALA is its ability to help you lose weight.

A 2018-systematic review and meta-analysis of clinical studies studied about ALA supplementation. It showed that it could help decrease weight in overweight subjects, compared to that of a placebo.

The same happened in another analysis wherein body mass index (BMI) and weight were reduced in obese individuals. (1, 2)

The antioxidant effects of ALA make it an ideal option to improve several health conditions too.

These antioxidant activities involve scavenging oxygen (ROS) and nitrogen species (RNS).

Others are regeneration of other antioxidants, metal chelation, and activation of antioxidant signaling pathways. It also influences the inhibition of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX). (1)

Another reason why ALA is beneficial is its ability to reduce signs of aging, such as skin roughness, wrinkles, and fine lines. It helps protect against skin damage while increasing the levels of some antioxidants, including glutathione. (1, 2)

ALA also protects the skin from the damage caused by radiation. This is due to its potent antioxidant effect. (1)

What is more, ALA has been suggested as a treatment for diabetes too. This is because of its ability to reduce blood sugar levels in both humans and animals. (1)

The approval of using lipoic acid for treating diabetic neuropathy has been confirmed in Germany. The research alone was mainly conducted in the said country. (1)

It is also said to reduce the risk of diabetic retinopathy (eye damage). (1, 2)

ALA has beneficial properties to your heart health as well. It helps in lowering levels of LDL “bad” cholesterol and triglyceride. (1)

With the antioxidant properties of this compound, you can have a lower risk of heart disease. It is through its way of reducing oxidative stress and neutralising free radicals. (1)

Last but not the least, ALA is also responsible for promoting healthy nerve function.

Based on a review of studies in 2012, a reduction of neuropathic pain was manifested because of 600 milligrams ALA, taken intravenously on a daily basis for over three weeks. (1)

In other cases, the progression of the early stages of carpal tunnel syndrome can be delayed. (1)

As of today, no other countries have yet approved the usage of ALA in treating diabetic neuropathy, except Germany. Yes, the results of several science-backed studies may sound promising. Nevertheless, a recommendation from a health expert is still necessary.

What is Alpha-Lipoic Acid?

Alpha-lipoic acid (ALA), is an organic compound produced naturally by animals, plants, and human beings. It is also known as thioctic acid. (1)

It is found in all cells of a human body, particularly in the mitochondria. (1)

However, it can also be obtained through supplements and foods.

ALA is a sulfur-containing, potent antioxidant in the body. The digestive tract swiftly absorbs it, usually being dissolved in both fat and water in the body.

Since it is synthesised in the body through a series of biochemical processes, yours can produce all the ALA it requires as long as it is healthy.

What if the body can only produce small amounts? Dietary supplements and foods rich in this antioxidant may help supply your body.

How Does Alpha-Lipoic Acid Work?

The main role of ALA is aerobic metabolism. This is the conversion of blood sugar into energy with the use of oxygen.

As antioxidant, free radicals that are damaging to human cells can be neutralised. It helps improve nerve function, decelerate skin aging, lessen inflammation, and reduce blood sugar levels.

In other countries like Germany, it is available by prescription and recommended for treating diabetic neuropathies. (1)

Being soluble in both fat and water, it can work in each cell in the body – and not all nutrients are like this. Some are only fat-soluble, while others are considered to be water-soluble. (1)

In addition, it helps in the restoration of glutathione, vitamin E, and vitamin C.

When a free radical is neutralised by these three, they become unstable and turn into free radicals themselves. That is why they need to be restored with the help of Alpha-lipoic acid.

When excess electrons were absorbed by ALA, they are converted back to their usual form.

How Do I Take Alpha-Lipoic Acid?

ALA can be found in foods, such as rice ban, carrots, yams, brewer’s yeast, and peas. Others are Brussels sprouts, spinach, tomatoes, broccoli, potatoes, organ meats, red meat, etc.

Aside from food sources, dietary supplements (capsules and tablets) containing ALA are also available. It can be given intravenously (IV) or as an injection too.

Safe doses without side effects have been noted between 300 to 600 milligrams. Still, it may vary based on the doctor’s prescription and what is written on the product label.

Typically, ALA should be taken 30 minutes before a meal. Its bioavailability will decrease if consumed together with a meal. (1)

Taking 50 to 600 milligrams ALA is probably greater than the amounts you can get in foods.

Can I Take Alpha-Lipoic Acid Along with Vitamins and Medicines?

ALA might interact with other medications for cancer (chemotherapy), thyroid disease, and diabetes (antidiabetic drugs).

Some nutrient interactions may take place too. A certain study suggests that ALA can compete with biotin because they have the same chemical structure. (1, 2)

Also, avoid taking other herbal supplements that tend to lower blood sugar levels along with ALA. These include Siberian ginseng, psyllium, Panax ginseng, horse chestnut, guar gum, fenugreek, and devil’s claw.

Some other interactions include iron salts, cisplatin, calcium salts, and alcohol (ethyl).

Is Alpha-Lipoic Acid Safe?

ALA has slight to no side effects. That is why it is safe for most individuals. Few cases experienced itching, rashes, nausea, and other negative reactions.

It is also not advised to take higher doses because of little information regarding its safety.

In animal research, negative effects were recorded due to exceedingly high doses.

Also, a 14-year old girl had a multiorgan failure resulting in death due to an overdose of ALA.

Children, pregnant, and breastfeeding women should ask first their healthcare provider before using ALA supplementation.

How Will Alpha-Lipoic Acid Benefit Me?

The levels of ALA in foods may be too low. That is why supplements are recommended because they provide 1,000 times more ALA than foods containing this antioxidant. (1)

Undoubtedly, this naturally-occurring organic compound is an important help your body needs to keep healthy wellbeing.

Start supplementing with Alpha-lipoic acid now!

YUUTO® DESTRESS ANTI-ANXIETY/STRESS*

Helps Body Adapt to Stress of Daily Life*.

Yuuto® DESTRESS Anti-Anxiety Formula Box

Features:

  • Helps promote a healthy response to everyday stress, over-work and fatigue;*
  • Helps support normal levels of mental clarity, concentration and alertness;*
  • Helps support normal levels of vigor and performance.*
  • Purity tested and allergen free;
  • Formulated by professionals;
  • 100% satisfaction – money back guarantee.
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